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New Business Owner Chris Greene Buys Alloy Printing, Opens Minuteman Press Franchise in White Plains, NY

Minuteman Press International Inc

In April of 2023, Chris Greene made the decision to switch gears and become a business owner. That is when Chris purchased over 40-year business Alloy Printing from Mary Jane and Alan Goldman, which is now operating as the new Minuteman Press franchise in White Plains, NY. The business remains located at 190 East Post Rd., White Plains, NY 10601, a 6,000 sq. ft. facility where it has been operating since 1995. Since buying the business, Chris has already hit several key milestones for Minuteman Press in White Plains. He attributes his sales growth to picking up where the previous owners of Alloy Printing left off – by joining local business organizations and maintaining existing client relationships. Chris has also been building on his established client base by marketing additional products and services such as custom branded apparel. History of Alloy Printing Mary Jane Goldman first joined the printing industry in 1979 when she opened a PIP Printing location in Yonkers. She moved the center to its current location at 190 East Post Rd. in 1995, and then eventually transitioned the business to an independent operation, Alloy Printing. Prior to owning the business, Mary Jane worked as a nurse for 11 years before looking for a change. In a previous interview with The Examiner, Mary Jane explained, “My options were open. I was taking a sabbatical. I could always go back to nursing. My parents had friends that were in printing and did very, very well. And I decided that would be a challenge that I would like to take on.” After initially expanding to three locations, the Goldmans decided to focus only on their White Plains location, where they had been residents since 1987. Mary Jane shared, “Sometimes more isn’t always better.” Alan noted, “[White Plains] is the center of the county. It’s the county seat. It’s where all the action is.” During their years in business, Mary Jane and Alan were active in several local groups including the White Plains Downtown Business Improvement District and many more. New owner Chris Greene has followed their lead, saying, “I was just appointed to the Board of the White Plains Downtown Business Improvement District and am also a member of the Business Council of Westchester. I have found these groups to be very beneficial in terms of networking and building/keeping relationships.” One thing that has never changed in over 40 years is the fact that people need and use print. Alan shared with The Examiner, “We’re supposed to be a more paperless society. But we find it’s not a paperless society.” In the interview, he added, “The internet doesn’t serve what we produce. We’re more of a hands-on, come in, sit down, let’s go over it. What can we do? How can we help? How can we both work together to produce what you want and make you successful? Because if you’re successful, we’re successful.” Welcome to Minuteman Press, White Plains Prior to buying the business, Chris Greene worked in corporate advertising, sales, and marketing. Chris shares, “The three biggest reasons I chose to buy Alloy Printing and transition to Minuteman Press are: My desire to be a business owner and move out of the corporate world; I look at the printing industry as an offshoot to what I was doing in my advertising career; The quality of my experience in learning about Minuteman Press and Alloy Printing.” Chris adds, “The training and support from Minuteman Press has been great. The training helped me develop a solid base of knowledge on how to operate a print business. When I’ve needed support in terms of learning or ramping up my marketing, my RVP Jim Galasso and the entire team have been great in giving me direction. It has been a positive experience all the way around.” When reflecting on the first six-plus months, Chris shares, “When I first started, my number one priority was to reassure our existing customer base that the high quality and customer service that they previously had was not going anywhere. As we look towards further growth, the first area we’ve grown from a product standpoint has been apparel, which we are actively marketing.” He adds, “For me, it’s not about being the boss as much as it’s about how I am spending my day. I enjoy giving our customers the products that we make. That the finished products are directly associated with my ownership of the business is very rewarding.” Minuteman Press in White Plains is located at 190 East Post Rd., White Plains, NY 10601. For more information, visit their website: https://minuteman.com/us/locations/ny/white-plains Learn more about #1 rated Minuteman Press franchise opportunities and read Minuteman Press franchise reviews at https://minutemanpressfranchise.com To learn about selling your printing business through Minuteman Press at no cost or broker fees to you, visit https://sellyourprintingbusiness.com Contact Details Minuteman Press International Chris Biscuiti +1 631-249-1370 cbiscuiti@mpihq.com Company Website https://minutemanpressfranchise.com

October 30, 2023 10:00 AM Eastern Daylight Time

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Crisis Protection Network Rebrands as “Reputation Advisors International”

Reputation Advisors International

The Crisis Protection Network, a worldwide association of distinguished communications professionals, today announced its new name: Reputation Advisors International The name change, which was adopted at the Network’s annual meeting in London on October 12, 2023, reflects the broadening scope of the Network as it looks to foster a “360-degree approach” to reputation management and reputational risk mitigation. “Effective management of reputational risk is more than just planning and responding in the event of a crisis,” James F. Haggerty, President of Reputation Advisors International, said. “It requires the establishment and maintenance of reputation management protocols that ensure the preservation of trust, credibility and brand equity in a complex, global business environment.” Membership in the Network is composed of leaders at independent strategic communications firms who bring unparalleled depth and diversity of knowledge to their work. Network members have previously served in senior positions at some of the world’s largest public relations agencies, as well as in corporations, major media outlets, law firms, and governmental organizations. Through regular collaboration and consultations, members share knowledge and perspectives to ensure their clients receive thoroughly vetted strategies for brand development, reputation management, and crisis and litigation communications response. Among the topics discussed at the Network’s annual meeting in London was effective communications training and response to cyber crises (including ransomware attacks), the role of the European Union in setting global standards in such areas as competition, energy and the environment, and current conditions in the APAC (Asia-Pacific) region. Network members also discussed reputation management issues in sports, as well as energy, the environment and the role of ESG (Environment, Social and Governance) principles in effect brand management. Haggerty added: “Through Reputation Advisors International, our member firms bring a depth of experience and breadth of resources that we believe is unrivaled by any strategic communications organization of its kind worldwide.” The Network currently has members in 16 cities across the globe, including Brussels, Chiasso, Chicago, Dublin, Frankfurt, Geneva, London, Los Angeles, Melbourne, Munich, New York, Oslo, Singapore, Sydney, Toronto, and Zurich. To learn more about Reputation Advisors International, visit: www.reputationadvisors.net. Contact Details Reputation Advisors International Juliette Foyle +1 212-683-8100 jfoyle@prcg.com Company Website https://reputationadvisors.net/

October 30, 2023 10:00 AM Eastern Daylight Time

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QYOU India's QPlay+ Expands Connected TV Distribution Via Global Partnership with Coolita

QYOU Media

Contact Details Doug Barker +1 437-992-4814 shareholder@qyoutv.com Company Website https://www.valuethemarkets.com

October 30, 2023 09:30 AM Eastern Daylight Time

Video

Realbricks Aims To Overcome Property Value Barriers In Real Estate Investing For Passive Income

Benzinga

By Faith Ashmore, Benzinga Begin your real estate investing journey on the Realbricks website! The COVID pandemic has arguably changed the real estate landscape in many ways, and the effects of the post-pandemic boom still persist. The vacation real estate market has experienced increased investment and growth in the post-COVID era. The pandemic led to a surge in interest and demand for vacation properties and more people now prioritize safe and private getaways. According to industry statistics, the vacation rental industry's market value increased by 22.76% from 2020 to 2021. With the low-interest rate environment during COVID-19, many Americans took advantage of the favorable conditions and invested in vacation properties. Sales of vacation homes surged, outpacing the growth in total existing home sales in 2020. The National Association of Realtors reported a 16.4% rise in vacation home sales in 2020, compared to a 5.6% growth in total existing home sales. At the beginning of 2021, about 60% of properties were sold above their advertised prices as a result of the "race for space" among homebuyers. However, many claim that is not just the vacation real estate market that is experiencing growth. Despite some ups and downs in the market, more and more people are looking to rent which makes investing in the rental real estate market attractive. Approximately 41% of Americans are choosing to rent, and rental properties are experiencing an increase in demand based on migration patterns. The apartment rental market in the U.S. was worth $258.4 billion in 2022 and has displayed consistent growth over the past five years. The U.S. alone makes up over 10% of the world’s residential value at an estimated market size of $2.53 trillion in 2023 and is also the world’s largest commercial property market. But even though the market is attractive in many ways, a large portion of investors have historically only had limited access to it due to barriers to entry such as the high amount of investment required – until now. Realbricks is a proprietary technology company that has recognized the increased interest in real estate and aims to democratize real estate investing. The company created a platform that makes real estate investment accessible to anyone, anywhere, empowering individual investors to participate in the real estate short-term rental market. The company seeks to enable people to express their interest in investing in vacation rentals like Airbnbs, long-term rentals, and multifamily properties without ever having to talk to a realtor. Its fractionalized approach to real estate means investors can express their interest to fractionally own rental homes, vacation rentals, and specialty furnished properties that they would otherwise not have access to. Traditionally, real estate investment has been limited to those with significant financial resources and industry connections. Realbricks seeks to disrupt this paradigm by allowing investors to build their real estate portfolios "brick by brick," enabling fractional ownership of properties. Realbricks believes that democratizing real estate investment not only benefits individual investors but also has positive social and economic consequences. The company says that opening up real estate investment to a wider population can support the growth of local communities. As more people invest in properties, Realbricks believes neglected neighborhoods can undergo revitalization, leading to improved living conditions, increased employment opportunities, and enhanced urban development. Expanding investment opportunities also empowers individuals to take control of their financial futures. Real estate has the potential to generate passive income streams and build wealth over time. By enabling more people to invest in real estate, we provide them with an additional avenue for financial security and independence, reducing their reliance on traditional employment and fostering economic empowerment. At the heart of Realbricks' philosophy is its commitment to simplicity and security. The company aims to have its platform prioritize user experience, offering a straightforward login and setup process that caters to both seasoned investors and newcomers to the investment world. However, the company has taken steps to ensure this emphasis on simplicity does not compromise security. All user data is encrypted, and Realbricks aims to provide users with peace of mind as they explore the wide range of fractional investment opportunities available on the platform. To learn more about Realbricks, click here. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

October 30, 2023 09:25 AM Eastern Daylight Time

Visa, Inc. Chairman Al Kelly Asked to Revoke Black Lives Matter Endorsement

NLPC

The following letter was sent today by Peter Flaherty, Chairman of the National Legal and Policy Center, to Alfred F. Kelly, Jr., Executive Chairman of Visa, Inc.: The Visa Inc. website still carries your July 15, 2020, endorsement of Black Lives Matter (BLM). We ask that it be taken down. We raised the issue of your BLM support at the 2023 Visa, Inc. annual meeting, but you ignored us. In the wake of the October 7 Hamas attack on Israel, BLM has shown its true colors. There is more than one entity that calls itself BLM, but the movement has made it clear where it stands. Please be aware: The Chicago chapter of BLM Grassroots tweeted imagery of a hang glider with a Palestinian flag, captioned “I Stand With Palestine.” Hang gliders were used by Hamas terrorists in the murder and hostage taking of innocent civilians attending the Tribe of Nova music festival. The BLM Grassroots national organization issued a “Statement in Solidarity With the Palestinian People” against the backdrop of the Palestinian flag. It read in part, “When a people have been subject (sic) to decades of apartheid and unimaginable violence, their resistance must not be condemned, but understood as a desperate act of self-defense." BLM Global Network Foundation (BLMGNF) co-founder Patrice Cullors, called for an “end of the imperialist project known as Israel” at Harvard Law School in 2015. Additionally, as detailed in a series of Complaints we filed with the Internal Revenue Service, BLMGNF is plagued by high living and self-dealing by its past and present leadership. Cullors, a self-proclaimed Marxist, resigned after we exposed the fact that she owned four homes. In the past, you have been eager to involve Visa, Inc. in controversial issues that have nothing to do with the company’s core business, but you have not yet condemned the Hamas attack or antisemitism. We ask that you do so without further delay. ### Contact Details National Legal and Policy Center Dan Rene +1 202-329-8357 drene@nlpc.org Company Website http://www.nlpc.org

October 30, 2023 07:40 AM Eastern Daylight Time

News Release

Connected TV Boom Creates Far-Reaching Opportunities

QYOU Media Inc

ValueTheMarkets News Commentary - In recent years the smart TV market has evolved from traditional digital TVs to more intelligent versions. Now there is a range to choose from with operating systems split between mainstream brands' own systems and open-source operating systems. This article discusses the opportunities this setup affords to a variety of companies including Sony Group Corp (NYSE: SONY), Microsoft (NASDAQ: MSFT), Roku (NASDAQ: ROKU), and QYOU Media (TSXV: QYOU) (OTCQB: QYOUF). Companies providing hardware that forms part of the Connected TV (CTV) landscape include Sony Group Corp, Microsoft, and Roku. Meanwhile, open-source operating system (OS) providers like Coolita in India have companies like Panasonic, Croma Electronics and French consumer electronic brand Thomson using its OS. The rise of major hardware and open-source OS providers in the CTV space creates significant opportunities for small and medium-sized businesses in the media and entertainment sector. For starters, the widespread adoption of CTV platforms expands the potential audience for these businesses, making it easier to get their content in front of viewers who are increasingly cutting the cord with traditional TV. QYOU Media (TSXV: QYOU) (OTCQB: QYOUF) is one such company that operates in India and the United States. Coolita recently partnered with QYOU India's QPlay+ to expand its Connected TV distribution via a global partnership. As a part of this strategic alliance, Coolita users in India and across the globe, through their wide range of smart TV sets, including COOCA, METZ, Panasonic, Croma, Thomson and others, will have simple access to stream QYOU Media India's growing portfolio of FAST channels – including The Q, The Q Kahaniyan, Q GameX, Sadhguru TV, and Bollywood Hungama Live on a free ad-supported basis. Early on, Coolita recognized an opportunity for a cost-efficient, user-friendly, and flexible OS in a receptive market. Indeed, the Connected/Smart TV market is booming, with 90% of TVs sold in India last year being Smart TVs. Global ad revenues in this space also surged, hitting $25.9 billion and marking a 13.2% CAGR in 2023. This growth enhances the viewer experience by offering high-quality, localized content. Sony Group Corp (NYSE: SONY), through its Home Entertainment and Sound division, produces LCD televisions, home audio, Blu-ray Disc players and portable audio devices. When it comes to hardware, Sony's TV range is top-class. An 8K TV is four times sharper than a 4K TV and 16 times sharper than a standard 1080p HDTV. This high resolution allows for incredibly detailed and lifelike images, giving viewers an immersive experience. Typically, 8K TVs also incorporate advanced technologies like HDR, wider color gamuts, and faster refresh rates, elevating the overall picture quality. While 8K content is still limited, the TVs usually employ upscaling algorithms to enhance lower-resolution content. The Z9K from Sony stands as a premier 8K TV, epitomizing visual brilliance. Additionally, Sony's 2023 Bravia XR TVs bring forth superior image processing. All Sony TVs from 2023 run Google TV, which offers user-friendly navigation and integrates seamlessly with services from Apple and Amazon. Microsoft (NASDAQ: MSFT) aims to drive digital change using smart cloud and edge technology. Its goal is to help everyone and every business globally succeed. Microsoft's primary focus in the entertainment hardware space is its Xbox gaming console series. The Xbox consoles, while primarily designed for gaming, offer streaming capabilities and apps that allow users to access various streaming platforms, effectively turning them into a part of the Connected TV ecosystem. The Xbox serves as a multimedia device, allowing users to stream movies, TV shows, and other content in addition to playing games. In its fiscal 2024, Q1 earnings report Microsoft reported better-than-expected subscriber growth in Xbox Game Pass as well as first-party content, primarily due to the launch of a game called Starfield. Xbox content and services revenue increased 13% and 12% in constant currency, while Xbox hardware revenue declined 7% and 8% in constant currency. Roku ( NASDAQ: ROKU) introduced streaming to TV. It connects users to their favorite content, helps content creators grow and profit from their audiences, and offers advertisers unique ways to reach consumers. Roku TV TM models, streaming players, and related audio devices are sold in various countries, either directly or through licensing with TV brands. Roku's recent Video on Demand (VOD) Evolution study highlights Canadian TV streaming habits. Now, 75% of Canadian internet users choose TV streaming, making it the most favored TV source. Ad-supported TV streaming has seen a rapid rise, with 59% watching it in the past year, a significant increase from 42% the previous year. Additionally, 63% plan to watch ad-supported streams in the coming year. This shift benefits advertisers, offering better targeting and flexibility. Ad engagement on streaming platforms is high, with many viewers responding by visiting brand websites or seeking more product information. This study shows that TV streaming presents unique opportunities for advertisers to effectively reach their audience. The CTV landscape touches a multitude of companies, and Sony, Microsoft, Roku, and QYOU Media are just a few of them. Curt Marvis, CEO of QYOU Media continues to view the CTV space as a strong area for growth in India and beyond in the years ahead. He notes "the partnership with Coolita allows QYOU to further strengthen its digital presence on connected TVs in India while also offering unique curated channels to a global audience." IMPORTANT NOTICE AND DISCLAIMER PAID ADVERTISEMENT This communication is a paid advertisement. ValueTheMarkets is a trading name of Digitonic Ltd, and its owners, directors, officers, employees, affiliates, agents and assigns (collectively the "Publisher") is often paid by one or more of the profiled companies or a third party to disseminate these types of communications. In this case, the Publisher has been compensated by QYOU Media Inc. to conduct investor awareness advertising and marketing and has paid the Publisher the equivalent of one hundred and twenty five thousand US dollars to produce and disseminate this and other similar articles and certain related banner advertisements. This compensation should be viewed as a major conflict with the Publisher's ability to provide unbiased information or opinion. 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You acknowledge and accept this disclaimer and that, to the greatest extent permitted under applicable law, you release and hold harmless the Publisher from any and all liability, damages, injury and adverse consequences arising from your use of this communication. You further agree that you are solely responsible for any financial outcome related to or arising from your investment decisions. TERMS OF USE AND DISCLAIMER By reading this communication you agree that you have reviewed and fully agree to the Terms of Use found here https://www.valuethemarkets.com/terms-conditions/ and acknowledge that you have reviewed the Disclaimer found here https://www.valuethemarkets.com/disclaimer/. If you do not agree to the Terms of Use, please contact valuethemarkets.com to discontinue receiving future communications. INTELLECTUAL PROPERTY All trademarks used in this communication are the property of their respective trademark holders. Other than valuethemarkets.com, the Publisher is not affiliated, connected, or associated with, and the communication is not sponsored, approved, or originated by, the trademark holders unless otherwise stated. No claim is made by the Publisher to any rights in any third-party trademarks other than valuethemarkets.com. AUTHORS: VALUETHEMARKETS valuethemarkets.com and Digitonic Ltd and our affiliates are not responsible for the content or accuracy of this article. The information included in this article is based solely on information provided by the company or companies mentioned above. This article does not provide any financial advice and is not a recommendation to deal in any securities or product. News and research are not recommendations to deal, and investments may fall in value so that you could lose some or all of your investment. Past performance is not an indicator of future performance.ValueTheMarkets do not hold any position in the stock(s) and/or financial instrument(s) mentioned in the above piece. ValueTheMarkets have been paid to produce this piece by the company or companies mentioned above. Digitonic Ltd, the owner of valuethemarkets.com, has been paid for the production of this piece by the company or companies mentioned above. Contact Details ValueTheMarkets +44 141 530 4080 editor@valuethemarkets.com Company Website https://www.valuethemarkets.com

October 27, 2023 11:16 AM Eastern Daylight Time

James McDevitt, Head of Equity Sales & Trading at Roberts & Ryan, Inc., is selected by Irish America Magazine for its 26th Annual Wall Street 50

Roberts & Ryan, Inc.

Roberts & Ryan, Inc., America’s first Service-Disabled Veteran-Owned Broker Dealer, is proud to recognize James McDevitt for his selection to Irish America Magazine’s 26th Annual Wall Street 50. The magazine’s Wall Street 50 recognizes the outstanding accomplishments and success of the best and the brightest Irish American and Irish-born leaders of the financial industry. Mr. McDevitt will be honored at the magazine’s gala dinner on Monday, October 30, 2023, at The New York Yacht Club. Jim’s Irish heritage can be traced back to both sets of Grandparents who emigrated to the United States in the late 1920’s. The McDevitt side from County Derry, and the maternal side from County Clare. Ireland and all things Irish have always been highlighted at family events, the history, and the luck that found the family in NYC. Mr. McDevitt is head of Equities Sales & Trading, Capital Markets at Roberts & Ryan, Inc., with an expertise in equity trading. He is a graduate of Oneota State College in New York, where he received his Bachelor of Arts degree, with a focus on American History. He also studied Technical Analysis at the New York Institute of Finance. Jim was a specialist on the floor of the New York Stock Exchange (NYSE) for 25 years, rising to become a partner at MJ Meehan & Co, and then as a Senior Vice President with Bank of America Specialists. During his career, Jim managed the trading post for marquee NYSE listed securities including Citibank, Walmart, Colgate, Sprint, McDonald’s, and JP Morgan. Jim spent three years at Academy Securities as a Managing Director selling fixed income and equity services to Corporate Treasurers. Jim has been involved in a number of charities and is a Board Member of Roberts & Ryan, Inc. He resides in Long Branch, NJ with his wife Nancy. They have three children, Patrick, Jennifer, and Colin. About Roberts and Ryan, Inc. Roberts & Ryan, Inc. is a Service-Disabled Veteran Owned (SDVO) broker dealer providing services in debt and equity capital markets, equity and fixed-income secondary trading, as well as corporate access events. The firm was founded in 1987 by a United States Marine Corps Vietnam combat veteran and Purple Heart recipient. With over $1.8 million in committed donations since 2018, Roberts & Ryan is active in donating to charitable foundations that make significant positive impacts in the lives of veterans and their families, focusing on general wellness, mental health, and career transition. To learn more about Roberts & Ryan, please visit www.roberts-ryan.com. Contact Details Michael C. Del Priore +1 646-859-4061 mdelpriore@roberts-ryan.com Company Website https://www.roberts-ryan.com

October 27, 2023 09:00 AM Eastern Daylight Time

BingX Releases Comprehensive Update of 4th Quarter 2023 Crypto Analysis and Highlights STORJ

BingX

SINGAPORE - Media OutReach - 27 October 2023 - BingX, a leading cryptocurrency exchange, is excited to announce the release of the highly anticipated Version 2 of its 4th Quarter 2023 Crypto Report. This updated report offers an in-depth examination of cryptocurrency price analysis and spotlights high value projects, building upon the success of its predecessor. The reports anticipates increased volatility for Bitcoin in Q4 2023. However, the potential approval of ETFs and ongoing economic uncertainty in the U.S. suggest a Bitcoin rebound during the fourth quarter of 2023. Version 2 of the 4th Quarter 2023 Crypto Report by BingX provides detailed insights and updates into cryptocurrency market performance and uncovers some of the most promising projects in crypto space. Projects featured in this report include updates on ARB price, ANT price, AAVE price and STORJ price. The report suggests that 2024 and 2025 could potentially be the final bull markets for Bitcoin with significant price increases, especially in the sector of DeFi. BingX's Version 2 of the 4th Quarter 2023 Crypto Report builds on the success of its previous edition of Token Price Analysis V1, offering fresh insights into the dynamic cryptocurrency market. This comprehensive resource empowers investors and enthusiasts with expert analysis and information to make informed decisions with recent BTC price movements and general consensus. About BingX BingX is a leading cryptocurrency exchange offering spot, derivatives, grid, and copy trading services to users in over 100 countries and regions worldwide. With a user base of over 5 million, BingX facilitates connections between users, expert traders, and the platform itself in a secure and innovative manner. Contact Details BingX media@bingx.com Company Website https://bingx.com/en-us/

October 26, 2023 10:05 PM Eastern Daylight Time

How Elicio Therapeutics Is Taking A Different Approach To Treating Cancers Like Colon Cancer, Expected To Be The Leading Killer Cancer By 2030

Benzinga

By Jeremy Golden, Benzinga Founded in 2011, Elicio Therapeutics Inc. (NASDAQ: ELTX) strives to use precision vaccines, immunomodulators and cell-based therapies to assemble cancer-killing immune responses against both blood and solid tumors. Elicio’s proprietary Amphiphile or “AMP” platform differentiates the company through the development of cancer immunotherapies for patients with limited treatment options and often poor outcomes. As the foundation for the various vaccine candidates in the biotech company’s pipeline, the AMP platform will help Elicio combat cancer and other diseases. Groundbreaking Platform Therapeutic vaccines are designed to train the immune system to recognize and destroy cancer cells by targeting tumor-specific antigens. These molecules are present on the surface of cancer cells, allowing the immune response to differentiate them from healthy cells. Tumor biology is complex, and it is difficult to identify effective target antigens. This is, in part, because the tumor microenvironment suppresses immune activity. Differentiating itself from competitors, Elicio Therapeutics is attacking this challenge head-on by re-engineering the body’s immune response to defeat cancer with potent lymph node-targeted immunotherapies and vaccines. Elicio’s AMP platform combines expertise in materials science and immunology to develop novel immunotherapies, including cell therapy activators, immunomodulators, adjuvants and vaccines to treat many aggressive cancers. The platform was first developed in the lab of Darrell Irvine, Ph.D., whose work as a Howard Hughes Medical Institute investigator and professor at the Koch Institute for Integrative Cancer Research at MIT has put him at the forefront of the field. A clinical-stage biotechnology company, Elicio Therapeutics has developed multiple cancer vaccine candidates, including: ELI-002 for KRAS-driven cancers caused by a mutation of the KRAS gene; ELI-007 for cancers involving mutant BRAF gene; and ELI-008 for cancers involving p53 hotspot mutations. “Looking to the future, our focus is on developing ELI-002 as a treatment for mutant KRAS (mKRAS)-driven cancers,” Chief Executive Officer Robert Connelly said in June after a reverse merger with Angion Biomedica Corp. “We are conducting clinical studies evaluating the 2-peptide and 7-peptide formulations of ELI-002 and are encouraged by the interim data that will be presented at ASCO, supporting ELI-002’s potential clinical utility in patients with high relapse risk pancreatic and colorectal cancers.” Vaccinating Against Cancer The Pancreatic Cancer Action Network estimates that about 95% of pancreatic cancer patients have the KRAS mutation, an error in a protein in normal cells that has the potential to cause cancer. By specifically targeting the KRAS mutation, prominent in patients with pancreatic and colon cancer, Elicio Therapeutics’ lead asset, ELI-002, is more promising than others in the clinical trial phase. Though further studies are needed to confirm its efficacy, the shot could improve survival for colon cancer, expected to be the number one cause of cancer deaths for people between 20-49 years of age by 2030, and pancreatic cancer, which has just a 12% survival rate after five years. Unlike other experimental cancer vaccines in development, the shot won't have to be customized to each patient, making it more affordable and readily available. Preclinical trials have shown that Amphiphiles target and concentrate an array of different immunogens in the lymph nodes, resulting in tumor or pathogen-targeted immunity. In one trial, an Elicio Therapeutics vaccine was given to patients with pancreatic and colorectal cancers. The results were promising, with 77% of patients experiencing a reduction in biomarkers that show the persistence of tumors. 32% of patients completely cleared those biomarkers. Elicio Therapeutics seems to be leading the charge toward vaccination against cancer. By combining expertise in immunology and immunotherapy, Elicio is precisely targeting and fully engaging the lymph nodes, the site in our bodies where the immune response to cancer is orchestrated. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

October 26, 2023 09:25 AM Eastern Daylight Time

Communications

New Business Owner Chris Greene Buys Alloy Printing, Opens Minuteman Press Franchise in White Plains, NY

Crisis Protection Network Rebrands as “Reputation Advisors International”

QYOU India's QPlay+ Expands Connected TV Distribution Via Global Partnership with Coolita

Realbricks Aims To Overcome Property Value Barriers In Real Estate Investing For Passive Income

Visa, Inc. Chairman Al Kelly Asked to Revoke Black Lives Matter Endorsement

Connected TV Boom Creates Far-Reaching Opportunities

James McDevitt, Head of Equity Sales & Trading at Roberts & Ryan, Inc., is selected by Irish America Magazine for its 26th Annual Wall Street 50

BingX Releases Comprehensive Update of 4th Quarter 2023 Crypto Analysis and Highlights STORJ

How Elicio Therapeutics Is Taking A Different Approach To Treating Cancers Like Colon Cancer, Expected To Be The Leading Killer Cancer By 2030