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News Direct Hires Respected Industry Veteran Kim Deonanan to Lead Its UK and European Sales Efforts

News Direct

News Direct today announced the addition of newswire industry veteran Kim Deonanan to its sales team as European Regional Sales Manager. Kim previously spent more than 18 years with Business Wire, where she served successfully in roles ranging from UK Sales Manager to Group Vice President, Europe. She will be responsible for business development in the United Kingdom and throughout Western Europe. Kim brings a wealth of industry experience and significant professional relationships to News Direct and has earned a deep level of respect within the newswire space with colleagues, clients and competitors alike. “I was partly responsible for bringing Kim on board at Business Wire and I came to trust her immensely and admire her greatly for her dedication, professionalism and talent”, stated Gregg Castano, Founder and CEO of News Direct and former Business Wire president. “She is one of the most knowledgeable people I can think of when it comes to the newswire industry. We are extremely pleased and fortunate to be able to bring someone of her caliber to our team and we're very excited to have her spread the News Direct gospel throughout the UK and Europe.” News Direct is a technology-driven content distribution and amplification platform for PR, IR, corporate communications and marketing professionals. Our automated platform delivers a completely reimagined, modernized user experience for newswire users that has reshaped the industry landscape. Additionally, the company has expanded its offerings to include an array of technology-enhanced message amplification tools ranging from sponsored content to podcasting products, all from one online destination. Contact Details News Direct Gregg Castano gregg.castano@newsdirect.com Company Website http://www.newsdirect.com

September 28, 2023 09:36 AM Eastern Daylight Time

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Digitalbox CEO upbeat on outlook for 2024 despite challenging first half

Digitalbox PLC

Digitalbox PLC (AIM:DBOX) CEO James Carter speaks to Thomas Warner from Proactive after the digital media company published its interim results for the six months to 30 June 2023. Carter discusses the challenges faced by the business during the first half of the year, noting that despite forecasting a tough period, the company did finish ahead of its internal budget. Two primary issues were highlighted: the reduced traffic from major platforms like Google and Facebook and the risks of algorithm changes and content strikes. Carter cited an instance where Entertainment Daily was blocked from Google's Discover feed, resulting in a significant drop in traffic. Another challenge was a 95% reduction in page reach on Facebook for a post about a Netflix show. To address these challenges, he says Digitalbox has optimised its website performance and is pivoting towards on-platform video content distribution. The company also acquired assets from Social Chain during the post-period, boosting their social media following. Carter expresses optimism about the global ad market's recovery and hints at potential future acquisitions for Digitalbox. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

September 28, 2023 09:26 AM Eastern Daylight Time

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After Achieving 100% Cancer Remission Rates In Preclinical Studies, Starpax Magnetodrones Head For Human Trials

Benzinga

By Rachael Green, Benzinga Starpax Biopharma is preparing to start clinical trials this year with its patented Starpax cancer treatment platform across six unmet needs, including pancreatic, breast, colorectal, head & neck, uterus and prostate cancer. Solid cancers like the ones Starpax will focus on in the upcoming trials account for 89% of all cancer deaths – that’s largely due to the fact that solid tumors are so difficult to treat. But Micheal Gareau, Founder and President of Starpax Biopharma, is on both a public and personal mission to change that after the disease claimed the lives of two brothers and his father and his third brother and sister are presently under treatment for cancer. And he has an impressive team with deep expertise in the space around him to help achieve this goal. The non-exhaustive roster includes such notable names as André Monette, former President at Johnson & Johnson France, Dr. Lisa Matar, former President of Eli Lilly (Canada) and John Helou, former president of Pfizer (Canada), Dr. Jacques Jolivet, holder of the King Georges V Silver Jubilee Medal in Oncology, and Berthe Latreille, who recently retired as COO of JP Morgan Investment Bank in London, all active on the board of directors. Here’s how this never-seen-before cancer treatment platform works. Why Solid Cancers Are Harder To Treat Anticancer drugs are usually injected in the blood network. The drug needs to circulate in 60,000 miles of blood vessels hoping to reach the tumor. Unfortunately studies have demonstrated that just 0.7% of the cancer drug dose actually reaches the tumor while nearly 99% of this toxic agent continues to circulate in the rest of the patient’s body causing unwanted side effects. The second difficulty, after the drug reaches the tumor, is to be able to distribute the drug throughout its entire volume. As the tumor continues to grow, the blood vessels become chaotic, malfunctioning or collapse, creating hypoxic zones (low level of oxygen areas) and making it difficult to diffuse the drug throughout the whole volume of the tumor. Several studies around the world have demonstrated that 90% of the tumor volume receives little or no drug at all creating a major resistance to treatment that systemic chemotherapy or immunotherapy have never been able to solve. The Starpax technology has been conceived specifically to solve this resistance problem to treatment. How The Starpax Platform Is Aiming To Overcome Those Challenges Starpax combines the power of four scientific disciplines: microbiology, biochemistry, electromagnetism engineering and AI into a two-part platform – the Magnetodrones and the Polartrak – that work together to deliver cancer drugs directly into tumors, trap them inside the tumors and ensure the spread into every part of them. Starpax Magnetodrones are self-propelled bacteria that are injected directly into a tumor. The non-pathogenic bacteria can swim between tumor cells without the need of blood vessels and are capable of carrying a variety of different cancer drugs. They die about 30 minutes to an hour after injection. In order to ensure they are distributed in the entire volume of the tumor rather than just sitting near the injection site, Starpax uses magneto-aerotactic bacteria. That means they’re sensitive to very specific magnetic fields, and they naturally accumulate in low-oxygen environments. Their sensitivity to magnetic fields comes into play with the PolarTrak, a device inside which the patient is positioned, that creates unique magnetic fields. Instead of leaving the Magnetodrones free-floating throughout the patient’s body, the Polartrak creates a magnetic sphere around the tumor that contains the Magnetodrones and forces them to distribute throughout the tumor’s whole volume without circulating in blood vessels. The combined result of the PolarTrak and Magnetodrones is a platform that can deliver powerful cancer-fighting drugs directly into a tumor and ensure that they are spread throughout its entire volume. Results of preclinical trials, report 100% of the dose reached the tumor delivering 50 times more drug in the tumor with 800 less toxic molecules in the patient’s body, a major improvement over current systemic chemotherapy and immunotherapy. Subjects also reported a 100% remission rate with no significant side effects. Building on those groundbreaking preclinical results, Starpax is preparing to start clinical trials this year to test the patented cancer treatment platform in humans. During those trials, a cancer drug that has already been approved by the FDA and has been in use by humans for over 20 years will be attached to the surface of Magnetodrones. The company is planning to seek fast-track designation from the Food and Drug Administration (FDA) to help get this new technology to the patients who need it as soon as possible. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 28, 2023 09:15 AM Eastern Daylight Time

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This Company Is Using AI To Establish Trust In A Digitally Connected World

Benzinga

By Faith Ashmore, Benzinga In today's increasingly digital world, the prevalence of fraud is a growing concern. The rapid advancement of technology and the widespread use of the internet have created new opportunities for unscrupulous individuals to exploit unsuspecting individuals and organizations. With the convenience and anonymity offered by the digital space, scammers can carry out illegal activities from anywhere in the world with greater ease than ever before. From online identity theft to phishing scams, digital fraud has become more sophisticated, making it harder for people to detect and protect themselves. The sheer volume of personal and financial information being shared online also increases the risk of data breaches and unauthorized access. Trust Stamp (NASDAQ: IDAI) is a company looking to revolutionize digital security and increase its penetration. The company is a global provider of AI-powered, privacy-first trust and identity services used across multiple sectors – such as banking and finance, real estate, communications, regulatory compliance and government. Trust Stamp offers a range of innovative services. Their biometric capture and analysis technology enables secure and convenient identity verification, allowing businesses to streamline onboarding processes. By integrating advanced document verification, Trust Stamp helps verify the authenticity of important documents, reducing the risk of fraud. In the face of increasing threats, Trust Stamp also provides cryptocurrency security and compliance solutions. Their expertise in this area assists businesses in safeguarding their digital assets, ensuring compliance with regulatory frameworks and protecting against unauthorized access or misuse. By facilitating accurate and reliable identity verification, Trust Stamp helps build trust between parties engaging in digital transactions, fostering secure interactions in a digital world. Unlike other companies that may enable AI to make complex decisions regarding users' authentication and identification, Trust Stamp has constructed a process that uses ML and various metric and statistical methods to audit the AI system. Their AI is used to extract information needed for identity verification but does not make the final decision, which helps to ensure that all decisions made using their systems are transparent and auditable. While Trust Stamp’s mission is similar to companies like Mitek (NASDAQ: MITK) and Nuance Communications (NASDAQ: NUAN), Trust Stamp has developed a proprietary process for tokenizing identity using an irreversible transformation via a convolutional neural network, creating an identity token known as IT2. The IT2 is generated by these AI processes, and data is removed and destroyed, making the token safe to store and reuse in the future. This process allows Trust Stamp to offer two unique value propositions to its customers: reauthentication and deduplication. Reauthentication enables users to reauthenticate using biometrics with ease, and deduplication allows for deduplication at scale to prevent synthetic identity fraud. Additionally, Trust Stamp is utilizing AI to improve the capture process and enhance users' experience. Its work focuses on using AI and language models to dynamically instruct users on how to take a quality picture, guiding them on the necessary changes to phone position, lighting and head position, among other parameters. This technology not only makes facial matching accessible to those with special needs but also vastly reduces bias in outcomes from AI-powered decision processes. As the digital landscape continues to evolve, Trust Stamp's emphasis on privacy and data protection is aimed at ensuring that users’ personal information is safeguarded at all times. By providing secure and trusted identity services, Trust Stamp positions itself as a crucial ally in the ongoing battle against fraud and identity-related issues, supporting a safer and more secure digital environment for all stakeholders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 28, 2023 09:15 AM Eastern Daylight Time

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Locality Appoints John Brohel as Chief Financial Officer

Locality

Locality, the industry’s preeminent local television solutions provider, today announces the appointment of John Brohel as Chief Financial Officer. Brohel brings 30+ years of experience in global financial and strategic planning to his new role, and has proven to be a key player in the accelerated growth of major entertainment studios. He will play a crucial role in Locality’s investments in technology, people, and products related to solving the needs of advertisers and inventory owners across local broadcast and streaming advertising. He will report directly to Ann Hailer, president of broadcast, and Keith Kazerman, president of streaming at Locality. Brohel joins Locality from AMC Networks where he was executive vice president of finance and responsible for global financial and strategic planning, as well as overall financial management of AMC International business units. Prior to AMC, Brohel held the position of chief financial officer at Leftfield Entertainment. There, Brohel led the financial management of the company's four business units — Leftfield Pictures, Sirens Media, Loud TV, and Outpost Entertainment. “This is an exciting strategic addition to our team,” said Ann Hailer, president of broadcast at Locality. “John’s expertise in financial planning and building structured processes for overall financial success for companies will play a pivotal role in the continued growth of Locality and in turn, our clients.” Keith Kazerman, president of streaming at Locality, added, “John's vast experience, particularly within the entertainment sector, positions us strongly as we bridge the traditional and digital realms within local video. His strategic approach to value creation and financial management will be instrumental in realizing Locality's long-term vision.” “I’m excited to join the Locality team as chief financial officer,” said Brohel. “Locality is committed to increasing collaboration across streaming and broadcast. As chief financial officer, I’m in a unique position to help the company develop new opportunities for clients and drive more dollars to local TV by investing in the right tech, people and products that push our solutions forward.” About Locality Locality is the industry’s preeminent local television solutions provider, committed to addressing the evolving needs of advertisers by unlocking the power of local and driving dollars to the local video marketplace. Locality brings together the best talent in both broadcast and streaming helping brands tap into the mindset of the local consumer and precisely reach optimal markets, nationally. Having served more than 1,500 ad agencies and 4,500 advertisers, to date, Locality offers the best premium inventory that the industry has to offer to help brands optimize their spend and target audiences at scale. Our team resides in 11 office locations across the U.S. designed to strategically service 100% of DMAs. For more information, please visit www.locality.com. Contact Details Julia Worthington +1 973-722-7881 julia@kitehillpr.com

September 28, 2023 09:00 AM Eastern Daylight Time

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Goodway Group Secures Spot on Newsweek’s Top 100 Most Loved Workplaces List 2023

Goodway Group

Goodway Group has been named to Newsweek’s Top 100 Most Loved Workplaces for 2023, ranking #65 among U.S. companies that have successfully established a workplace culture characterized by respect, inspiration, appreciation and employee-centric values. This annual ranking is a result of Newsweek 's collaboration with the Best Practice Institute (BPI), a renowned leadership development and benchmark research company. Results were determined based on a comprehensive survey that included feedback from over 1.4 million employees across different-sized businesses, with workforces ranging from 50 to over 10,000 employees. Based on BPI's Spark Model, the analysis evaluated key areas such as Systemic Collaboration, Positive Vision of the Future, Alignment of Values, Respect and Killer Achievement. Factors like employee engagement, workplace positivity and commitment to the organization's success were carefully considered to identify the Top 100 Most Loved Workplaces. “At Goodway Group, we pride ourselves in how we navigate change, foster a growth mindset and set ourselves and our clients up for continued success. We believe this recognition is a genuine testament to our unwavering dedication to maintaining an award-winning remote work culture – one that puts transparency and employee well-being above all else,” said Kandi Gongora, Chief Transformation and People Officer at Goodway Group. “We strongly believe our success is intertwined with our employees’ success. That’s why our infinity loop approach ensures our people feel valued, supported and empowered so they in turn can provide the highest level of service to our clients.” Our fully remote team comes together twice a year for an incredible week-long experience in a different U.S. city where employees can learn, collaborate for strategic alignment and build meaningful connections. And that's not the only way we bring our team together – all our employees receive an Oculus headset upon hire and are encouraged to participate in virtual team-building activities throughout the year. At Goodway, we understand the importance of ongoing education to stay relevant and ahead of the competition, which is why we offer employees a comprehensive learning platform, a $1,500 personal learning budget each year, tuition reimbursement and even set aside a day each month for employees to focus solely on upskilling and building future-ready skills. We believe investing in our employees' growth is crucial to providing our clients with the best possible outcomes. Amidst the hustle and bustle of modern corporate culture, Goodway also gives employees the opportunity to embrace the power of deep focus and uninterrupted productivity. With our innovative flex Fridays initiative, we recommend no internal meetings to provide our employees with ample time and space to dwell deeply on critical work projects, ideate new strategies or simply recharge their batteries. And unlike many holding companies that are moving employees to a hybrid work environment or back to the office full-time post-pandemic, this isn’t Goodway’s plan: We’ve been a remote workplace since 2006 – trailblazing this space long before it gained popularity in the pandemic era. “With the dynamic workforce and competition for top talent, more companies are recognizing the importance of employee engagement and commitment,” said Nancy Cooper, Global Editor in Chief, Newsweek. “The workplaces that have demonstrated a commitment to their employees in 2023 are more likely to attract top talent and deliver strong business outcomes.” "Attracting and retaining top talent continues to be a challenge and top priority of executive leadership,” said Louis Carter, CEO, Best Practice Institute. “The companies on this list have committed to listening intently to their employees and then creating a better workplace where employees love to come to work.” See Newsweek’s full 2023 Most Loved Workplaces list. Methodology To identify the top 100 companies for the Newsweek ranking, companies were evaluated and scored as follows: 35 percent of the initial score was based on employee survey responses; 25 percent was derived from analysis of external public ratings from sites such as Comparably, Careerbliss, Glassdoor, Indeed and Google; and 40 percent came from direct interviews with and written responses from company officials. Newsweek then conducted additional research into every company on the list, as well as the top runners-up, to determine the final list of 100 companies and their ranking. (The list includes both U.S. firms and companies with a strong U.S. presence that are based overseas.) To learn more about career opportunities at Goodway Group, please visit our Careers page. About Goodway Group Goodway Group is a leading data-driven and technology-enabled digital media and marketing services firm with teams in the U.S. and the U.K. Our diverse team of digital strategists, media practitioners, technologists and data scientists have won the most prestigious awards for innovative marketing technology, impactful work and inclusive remote-first places to work including being honored as a multiyear Ad Age Best Places to Work, AdExchanger’s Best Use of Technology by an Agency Award and three MarTech Breakthrough Awards. The firm deploys deep expertise across both consumer and B2B marketing, including brand-performance advertising, retail media and commerce, and advanced analytics using proprietary digital programmatic technologies, data, analytics methodologies, and consultation. Goodway Group is an independent and remote-first media and marketing services firm with a 90+ year history. Find Goodway Group online at Goodwaygroup.com or follow us on Facebook, X (formerly known as Twitter) or LinkedIn. Contact Details Julia Worthington +1 972-722-7881 julia@kitehillpr.com Company Website https://www.goodwaygroup.com/

September 27, 2023 01:41 PM Eastern Daylight Time

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Shopistry Launches White-Label eCommerce Platform Enabling Banks, Merchant Acquirers, and Payment Processors

Shopistry

Toronto, Ontario -- Shopistry, a leading commerce solution provider powering local merchants to leading brands, today announced the launch of Private Label Commerce, the industry’s first white-label eCommerce solution. Banks, merchant service providers, payment providers, and software companies can now offer merchants a modern, no-code online store and omni-channel solution, integrated with their existing offerings, growing client value, gaining revenue, and reducing churn. The innovative approach is designed to empower traditional fintechs to deepen client relationships and compete with software providers that are increasingly offering payments and financial products to business owners as a catalyst for growth. “Owning the customer relationship is critical and the more indispensable you become to your merchant’s business the better. This why eCommerce software companies have increasingly moved into payments, loans, and more, putting pressure on traditional fintech companies. Shopistry’s Private Label Commerce levels the playing field; it’s a game changer to offer your clients a Shopify-like solution without the work,” said Jaafer Haidar, CEO at Shopistry. Private Label Commerce is the latest from Shopistry and introduces a focus on small/medium businesses to compliment the company's existing products for leading brands and media and entertainment that powered growth at Oura Ring, Black Rifle Coffee, NEON and other leading brands. “We’re focused on running our business and needed a solution that’s easy and integrated with our payments and banking so we can manage everything in one place. We tried others but Shopistry is easy to use and has a lot of features. The fact that it’s offered by our payments company means we only have one place to go for anything we need,” said Matt Boom, partner at Boomerz Boxing & Fitness.” Shopistry has partnered with major merchant service providers and is now open for additional partners. Key benefits include: White-Label & Supported: End-to-End software, videos, managed support by Shopistry Sales Enablement Program: Sales support and training to enable your sales effort Turn-key Mobile & Web Stores: Merchants quickly start selling online Dynamic Checkout: Single-page checkout, integrated payments, BOPIS, Shipping more Simplified Operations: Automatic product, inventory, order, and payment integration enables seamless operations without changes to business processes Seamless Omni-channel: Integration with in-store terminals and systems to deliver a seamless omni-channel solution Continuous Innovation with AI, Social and more: Ongoing product innovation drive further value to clients, keeping partners ahead of the game without costs To learn more about how Shopistry Private Label Commerce can benefit your organization, please visit shopistry.com contact partners@shopistry.com. For press inquiries please contact press@shopistry.com. About Shopistry Shopistry commerce software and solutions empower partners and merchants of all sizes to innovate and grow their business online hassle-free. Shopistry powers SMBs to leading growth brands like Oura Ring, Honed, NEON Studios, and more with modern functionality, simplicity, performance, and flexibility to adapt and grow as commerce continues to evolve. To learn more visit shopistry.com. Shopistry® is a registered trademark of Shopistry Inc. Third-party trademarks and service marks are the property of their respective owners. Contact Details Bryanne Baker press@shopistry.com Company Website https://www.shopistry.com

September 27, 2023 11:58 AM Eastern Daylight Time

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How Altius Minerals Is Building An ESG-Compliant Portfolio With The Potential To Deliver Sustainable Royalties For The Next 100 Years

Benzinga

By Faith Ashmore, Benzinga As the United Nations wraps up its 78th General Assembly in New York City, the most pressing issue at hand has been putting the 17 Sustainable Development Goals (SDGs) back on track and aligning political agendas with the ever-important environmental goals. While governments will shape policy, companies have substantial sway in affecting the economy and direction of environmental action. ESG investing has been one of the fastest growing investment classes, even after public pressure around green-washing that occurred in 2022. This backlash has caused asset managers and regulators to be more cautious about what styles of investing get classified as ESG investments. This caution around using the term ESG more deliberately likely contributed to a report issued in 2022 by the US SIF, which classified $8.4 trillion in U.S. investment assets at the beginning of 2022 held by firms that factor ESG into their decision-making. Although this is a huge number, it’s less than half the $17.1 trillion assets that were classified as ESG assets under management in 2020. Altius Minerals (OTCQX: ATUSF) (TSX: ALS) has built an ESG-friendly royalty portfolio. Altius is part of the broader mining sector, an industry that has been under criticism for its long history of causing significant harm to the environment, from deforestation and habitat destruction to water pollution and greenhouse gas emissions. But materials that go into electronics, electricity generation, transportation and virtually all 21st-century lifestyle infrastructure are dependent on the mining industry. Altius is a royalty company that, unlike most of its competitors, has very little gold royalty exposure. Although gold has properties that make it uniquely adaptable for uses including medical and technology applications, its main demand source is jewellery and coins. Contrast that with copper, which along with potash, are Altius’s main exposures. Altius is working towards creating a portfolio that is sustainable. The company is targeting potash, electrification battery metals and iron ore for green steel, along with their core holding in subsidiary Altius Renewable Royalties (OTCQX: ATRWF) (TSX: ARR). These markets align with multiple UN sustainable development goals, such as eradicating poverty, ensuring renewable energy, responsible procurement and more. This strategic focus aligns with the values of stakeholders who believe in these goals. One significant aspect of Altius Minerals' sustainable portfolio is the emphasis on long mine lives. Unlike typical gold mines that run for 10-15 years, potash mines, for instance, are expected to have a lifespan of up to 100 years or more. This longevity ensures employment opportunities for entire careers or even generations. Long resource lives are also the best predictors of expansion opportunities. While potash mine lives can be long at 100+ years, renewable energy resources are potentially infinite, making the business of ARR unique in that the resource is never subject to depletion. That is a significant contrast to other energy forms, like shale wells. Revenue from Altius Renewable Royalties is accelerating, with new project royalties expected to be operational by 2024 from investments already made. Their commitment to renewable energy aims to align with the global transition towards cleaner and more sustainable energy sources. Altius claims it doesn’t avoid industries where emissions are considered “hard to abate” like steel-making. Altius wants its investments to fall on the side of steel-making that is sourcing high-purity iron ore for electric arc furnace steel making, aiming to eliminate the use of metallurgical coal inputs. Altius’s iron ore exposure is Labrador Trough iron ore, considered to be among the highest grade and lowest impurity sources globally. One of the most significant ESG transitions in the world, along with the energy transition, is the transition from internal combustion engine transport to electric vehicles. According to the International Energy Agency (IEA), electric car markets have witnessed exponential growth, with sales exceeding 10 million in 2022; 14% of all new car sales in 2022 were electric, a notable increase from around 9% in 2021 and less than 5% in 2020. The IEA further projects that the global market value of electricity for EV charging is set to grow significantly, reaching approximately $190 billion by 2030. The Climate Action Tracker report suggests that to align with the 1.5 degrees Celsius pathway, fully electric vehicles will need to account for 75-95% of global annual passenger vehicle sales by 2030 and 100% by 2035. This growth demonstrates the increasing demand for EVs and the need for the materials and infrastructure to support this growth. As an example, an electric vehicle uses almost 2.5 times the copper of a car with an internal combustion engine, and S&P Global forecasts that copper demand will nearly double between 2022 to 50 million metric tons and 2035 to 50 million metric tons. By 2050, demand will reach more than 53 million metric tons. To illustrate just how strong the demand growth is, S&P Global noted that that’s “more than all the copper consumed in the world between 1900 and 2021.” EV demand is similarly driving the need for mining of other materials such as lithium, which is commonly used in EV batteries. Copper is one of Altius’s largest royalty exposures. Mining producers of these critical materials will need financing partners who support the impact they’re making and their sustainability goals. Altius Minerals aims to position itself as a leading diversified royalty player with positive impacts on climate, electrification and food security, as well as a front-runner in the ESG space – an ideal financing partner for sustainable miners. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 27, 2023 09:15 AM Eastern Daylight Time

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With Cancer Immunotherapy Market Set To Grow At Double-Digit CAGR Till 2032, This Company Plans To Ride The Wave Through Treatments For Complex Cancers

Benzinga

By Faith Ashmore, Benzinga Oncotelic Therapeutics Inc. (OTCQB: OTLC) is a clinical-stage biopharmaceutical company. Its primary focus is on developing innovative drugs for the treatment of orphan oncology indications, with an emphasis on rare and underserved cancer types including pancreatic cancer, glioma and glioblastoma. Oncotelic's pipeline includes several promising drug candidates. One of their key products is OT-101, a targeted immunotherapy designed to inhibit the production of a specific protein critical for cancer evasion of host immunity. By targeting immune evasion specifically, OT-101 aims to reduce the effectiveness of traditional immunooncology (IO) drugs and improve patient survival. This drug has also been shown to be successful in helping treat immune evasion by COVID-19. Oncotelic is undertaking combination trials with IO drugs such as PD-1, PDL-1 and CTLA4, among others. Over the next 12 months, it is expected there will be reports available on these combination trials. In August, the company announced a collaboration between their joint venture partner, Sapu Bioscience, LLC (wholly owned by GMP Biotechnology Limited), and Cromos Pharma, LLC. This collaboration’s goal is to conduct a registrational trial for OT-101 in the treatment of pancreatic cancer. The company is expecting to report interim analyses in the near future. This trial leverages the ability of OT-101 to counteract chemoresistance that frequently arises during the treatment of cancers with chemotherapies. In many ways, OT-101 was designed to improve existing cancer treatments, such as Keytruda. Merck & Co’s (NYSE: MRK) Keytruda – also known as pembrolizumab – is an immunotherapy used to treat various types of cancer, including lung cancer, melanoma and triple-negative breast cancer. It blocks the PD-1 pathway, allowing the immune system to detect and fight cancer cells. What makes Oncotelic an industry innovator is its embrace of AI in its workflow. By leveraging AI, the company is mining its existing database to design the optimal clinical pathway for each of its drugs. Through their dedication to incorporating cutting-edge science and engineering, Oncotelic is positioning itself at the forefront of advancing novel drugs in oncology. In addition to OT-101, Oncotelic is advancing other drug candidates, as well, including CA4P and Oxi4503. These drugs utilize different mechanisms of action to target blood vessels feeding the tumors and disrupt their growth. This diversified pipeline strategy allows Oncotelic to explore multiple approaches to cancer treatment and increase the likelihood of success in addressing different types of cancer. By leveraging AI, Oncotelic's drug candidates can overcome the limitations of conventional clinical trials, avoiding unintended confounding factors that plague traditional clinical trials. Long before a clinical trial is initiated, extensive in silico modeling would have been completed at Oncotelic, derisking every aspect of the clinical trial and optimizing it for success. Oncotelic Therapeutics is an innovative player in the cancer immunotherapy market, which is expected to reach a value of $647 billion by 2032, growing at a CAGR of 13.8% over 2022-2032. The company has completed promising phase 2 trials in pancreatic cancer and melanoma, as well as in glioblastoma, achieving robust efficacy and safety in all three cases. With the company’s cutting-edge research and impressive track record, Oncotelic is setting the bar high for innovation in cancer treatments. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 27, 2023 09:15 AM Eastern Daylight Time

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