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Tomorrow in New York, A Seminar Opens the Gateway to Brazil’s Robust Market Opportunities

1BusinessWorld

The Brazilian-American Chamber of Commerce, in collaboration with the Instituto Brasileiro de Desenvolvimento de Relações Empresariais Internacionais (IBREI), is set to host an influential breakfast seminar that promises to unpack the labyrinth of opportunities in the flourishing Brazilian market. Titled "Opening the Doors to the Brazilian Market," this event stands as a pivotal rendezvous for business leaders aiming to penetrate or expand their footprint in South America's largest economy. https://brazilcham.com/event/opening-the-doors-to-the-brazilian-market/ Scheduled to convene at the Brazilian-American Chamber of Commerce's headquarters in Manhattan, the event is engineered to offer a comprehensive overview and insider knowledge of Brazil's diverse and intricate market. It will feature a cadre of experts and seasoned practitioners, providing attendees with the foresight needed to navigate and excel in a complex, yet rewarding business landscape. The first panel, moderated by James Rosenstein of 1BusinessWorld, promises an in-depth look at Brazil's economy, discussing entry strategies, sectorial overviews, and emerging opportunities. Notable speakers such as Luiz Flávio Cordeiro and Ramon Fernandez Aracil Filho will connect via Zoom, offering their expertise remotely, while Maurício Prazak will provide his insights in person. In the second panel, moderated by Jeff Levy, a senior figure in business development at 2H Software and advisor at 1BusinessWorld, the focus will shift to the tactical side of operations within Brazil. Attendees will be treated to case studies of U.S. companies that have successfully planted their flags in Brazilian soil, with valuable lessons on navigating the legal and regulatory challenges presented by the Brazilian business environment. “The Brazilian market is ripe with opportunity, yet it presents unique challenges that can be daunting for the uninitiated," says Maurício Prazak. "This seminar is tailor-made to equip business leaders with the knowledge and connections necessary to turn these challenges into profitable ventures." The event is a must for C-suite executives, entrepreneurs, and business developers looking to engage with one of the world's most vibrant economies. It's an opportunity to not only gain valuable insights but also to network with like-minded professionals and potential partners. The breakfast seminar underscores the chamber's commitment to fostering bilateral commercial ties and is a testament to the robust economic linkages that bind the U.S. and Brazil. “This seminar is more than just an event; it's a beacon for U.S. companies aiming to understand and succeed in Brazil,” said a spokesperson for the Brazilian-American Chamber of Commerce. “It embodies our mission to facilitate bilateral commerce and investment, and offers an exclusive platform for strategic engagement.” As international market dynamics continue to evolve, the seminar represents a timely and strategic conclave for those looking to diversify their international portfolios and align with the pulse of Brazil's economic prospects. Prospective attendees are urged to register early due to limited seating. The details of the seminar, including registration information and agenda, can be found on the Brazilian-American Chamber of Commerce’s website. Venue and registration information: Brazilian-American Chamber of Commerce 485 Madison Avenue, Suite 401 New York, NY, 10022 https://brazilcham.com/event/opening-the-doors-to-the-brazilian-market/ This in-person event is not only an investment in knowledge but also an invaluable opportunity to network with those who are shaping the future of U.S.-Brazilian trade relations. All news and content distribution in partnership with News Direct. The Brazilian-American Chamber of Commerce, Inc., based in New York City, is an independent, not-for-profit business membership organization. A non-governmental association, the Chamber’s mission is to promote trade, investment, and cultural ties between the two nations and to help develop closer ties between the business communities of both nations. The Chamber acts as a host to bring together audiences to learn about the latest developments and opportunities in Brazil. It is a source of information for both Americans and Brazilians regarding the latest business practices and facilitates interpretation and understanding of Brazil for the international business community. Brazilian-American Chamber of Commerce The Instituto Brasileiro de Desenvolvimento de Relações Empresariais Internacionais (IBREI) is a non-profit civil association that brings together individuals and companies, in different countries, aiming at national development. Its mission is to build bridges between professionals, companies and institutions, both public and private, improving the quality of the national and international business environment. Instituto Brasileiro de Desenvolvimento de Relações Empresariais Internacionais About 1BusinessWorld: 1BusinessWorld is a global business ecosystem, network and marketplace that provides entrepreneurs, business owners and professionals with the information, tools, resources and connectivity needed to succeed throughout their company’s growth journey, toward a better business world. Our vision is based on the reality that we live, work and do business in one global interconnected business environment, and hence our motto: “One World, One Business World”. Our mission is to encourage and support global communication and collaboration among entrepreneurs, professionals, and businesses. 1BusinessWorld Contact Details 1BusinessWorld Media Enquiries +1 212-220-6677 info@1businessworld.com Company Website https://1businessworld.com

November 06, 2023 11:23 AM Eastern Standard Time

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Minuteman Press Franchise Owner Nil Patel Talks Leaving Corporate World, Celebrates Grand Opening in Solon, Ohio

Minuteman Press International Inc

After working in corporate finance, Nil Patel was looking for a career change. He shares, “I previously graduated from the University of Cincinnati with a bachelor’s degree in finance. After 8 years in the corporate world, I realized it was not for me. I wanted to be part of a company that helps others and be somewhere I can feel gratitude from the work I do!” Nil found what he was looking for in June of 2023 when he purchased the Minuteman Press franchise in Solon, Ohio. He explains, “I chose Minuteman Press because I wanted to be a part of a small business that has potential to grow and help other business thrive around me. The training and support from Minuteman Press International has been great! My RVP Rich DeRosa in particular has been extremely helpful and professional.” In September of 2023, Nil celebrated his grand opening; Minuteman Press in Solon is located at 33528 Aurora Road, Solon, OH 44139. Nil shares, “The community of Solon is a diverse blue-collar town where people are proud of the work they do! Our grand opening was a huge success. It was put together by the Solon Chamber of Commerce and I received extra help from my girlfriend and parents to really bring it all together. I’m excited to continue to serve and be a contributing member of the Solon community.” A few months into owning the business, Nil is happy with his progress as a business owner. He says, “I explain to clients that Minuteman Press in Solon is a full-service design, print, and marketing center serving the entire business community from small businesses to Fortune 500 companies. Our client base and business have been steady and we are growing.” Nil adds, “High-demand products that can help other local businesses/organizations grow are business cards, banners, flyers, and promo products – pens, calendars, koozies, flash drives, etc.” When asked about the industry and what he enjoys the most thus far, Nil answers, “Printing remains vital today because physical and digital advertising are both continuing to grow and this trend is going to continue.” He concludes, “Clients are looking for a healthy mix of both and I love that I can grow my business while helping others grow as well.” Minuteman Press in Solon, Ohio is located at 33528 Aurora Road, Solon, OH 44139. For more information, visit their website: https://minuteman.com/us/locations/oh/solon Learn more about #1 rated Minuteman Press franchise opportunities and read Minuteman Press franchise reviews at https://minutemanpressfranchise.com Contact Details Minuteman Press International Chris Biscuiti +1 631-249-1370 cbiscuiti@mpihq.com Company Website https://minutemanpressfranchise.com

November 06, 2023 10:00 AM Eastern Standard Time

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How IN8bio Is Working To Reach Its Goal Of “Cancer Zero” – Making Cancer A Thing of The Past

Benzinga

By Ted Stavetski, Benzinga IN8bio Inc. (NASDAQ: INAB) is a clinical-stage biotechnology company tackling one of society’s most pressing issues: cancer. Specifically, the company is focused on using the immune system to eliminate residual tumors, and currently has two clinical programs focused on leukemia and on glioblastoma, the deadliest type of brain cancer. IN8bio is pioneering a new approach using the immune system to tackle the deficiencies that plague most current cancer treatments. Alpha-beta T cell-based chimeric antigen receptor, or CAR-T therapies have shown remarkable results against some leukemias and myelomas. However, many of these CAR-T treatments have faced challenges against more difficult-to-treat leukemias, such as acute myeloid leukemia (AML) and solid tumor cancers. These cancers can be highly heterogenous, making them difficult to kill since they are often intertwined in healthy tissues, leading to unintentional toxicities and adverse events. In some cases, patients have even died. Fortunately, IN8bio may have found the solution to this problem. What Is “Cancer Zero?” IN8bio set out on a mission that it calls “Cancer Zero”, which co-founder and CEO William Ho describes as “the goal of pursuing the safe eradication of all tumor cells in patients fighting cancer.” In other words, the company aims to eliminate all cancer cells without destroying healthy cells. To achieve this, the company has developed advanced technologies using a specific subset of immune cells, or lymphocytes called gamma-delta T cells, in its DeltEx platform. Gamma-delta T cells are white blood cells whose job in the body is to be a first-responder and to determine safe and not-safe. They kill invading or dangerous cells and can call in reinforcements by recruiting and activating other immune cells. It was IN8bio’s co-founder, Dr. Lawrence Lamb, a clinical immunologist on a cancer ward treating patients with aggressive leukemias in the 1990s, who made the first observation that gamma-delta T cells are linked to greater survival in cancer patients. He spent the next 25 years figuring out how to expand, genetically engineer and manufacture gamma-delta T cells at scale and into a cancer therapy. In 2016, IN8bio was launched to take these gamma-delta T cell technologies into the clinic and today, Dr. Lamb is IN8bio’s Chief Scientific Officer. He leads a team of scientists and researchers dedicated to achieving the company’s mission of Cancer Zero. IN8bio’s DeltEx platform uses gamma-delta T cells that it believes are potentially safer and more effective at killing cancer cells than other therapies currently in development. The company has the capability to utilize autologous (from the patient), allogeneic (from a donor or “off-the-shelf”) and induced pluripotent stem cell (iPSC)-derived gamma-delta T cells. These cells can be expanded, activated and genetically engineered outside of the body to increase their numbers and to enhance their hunting and killing abilities. In one platform unique to IN8bio, its drug resistant immunotherapy (DRI) technology enhances gamma-delta T cells by genetically engineering them to be chemotherapy resistant. Chemotherapies have been a mainstay of front-line cancer therapy since World War II. While effective at shrinking a tumor and prolonging survival, they also kill white blood cells. As a result, microscopic residual tumors that are resistant to therapy often remain and result in relapse because of the weakened immune system. IN8bio’s DRI approach allows the simultaneous combination of chemotherapy with an immune therapy that may create synergies that allow the DRI gamma-delta T cells to recognize and eliminate the residual tumor cells while leaving healthy tissues alone. By targeting compartments of residual tumor cells, IN8bio’s DRI approach may achieve deeper tumor responses that can prolong survival. The company has already protected the DRI technology behind this process with issued patents around the world. IN8bio: Drugs In Clinical Development IN8bio has three therapies that are in varying stages of clinical development: INB-400: A phase 2 multi-center clinical trial for the treatment of newly diagnosed glioblastoma, or GBM ( NCT05664243 ). This trial has recently initiated enrollment at leading brain tumor centers across the United States following clearance of a company-sponsored investigational new drug application, or IND, by the U.S. Food and Drug Administration, or FDA. This program received Orphan Drug Designation (ODD) from the FDA in the spring of 2023 for targeting a significant unmet medical need, which offers potential incentives such as 7-year market exclusivity. INB-200: A phase 1 clinical trial at the University of Alabama at Birmingham using autologous, genetically modified DRI gamma-delta T cells for the treatment for newly diagnosed glioblastoma (UAB - NCT04165941 ). This program was one of only four central nervous system (CNS) cancer programs to have received an oral presentation at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting, the largest world-wide yearly gathering of cancer clinicians and researchers. At that time, the company released initial phase 1 data showing that 100% of treated patients have exceeded expected median progression-free survival. An additional clinical update is expected in November 2023 at the Society for Neuro-Oncology Annual Meeting (SNO), and long-term follow-up data is expected to be presented at medical meetings in the first half of 2024. INB-100: A phase 1 trial for the treatment of patients with high-risk leukemias undergoing haploidentical stem cell transplantation, or HSCT ( NCT03533816 ). The company presented a clinical update at the European Society for Blood and Marrow Transplantation (EBMT) annual meeting in April 2023 that demonstrated 100% of evaluable patients (n=7) treated with INB-100 remained alive, progression-free and in durable complete remission (CR) as of April 21, 2023. Patients included high-risk AML patients and a patient with acute lymphoblastic leukemia (ALL) who had failed four prior lines of therapy, including CAR-T. All evaluable patients remained alive as of the last assessment and one patient had survived for three years. IN8bio has completed primary enrollment of the phase 1 clinical trial, with updated results expected at the American Society of Hematology (ASH) Annual meeting in December 2023. Topline long term follow ups are expected in 2024. To further its research, IN8bio recently opened a new 10,000-square-foot research & development (R&D) facility in Birmingham, Alabama. This state-of-the-art facility not only bolsters the company’s ability to advance its groundbreaking pipeline of gamma-delta T cell therapies, but also further taps into the advanced cancer research at the UAB, and other prominent institutes. Additionally, the company holds a total of 19 granted U.S. and international patents with many more still pending approval. This will help IN8bio protect its innovative new therapies from competitors as they proceed through clinical trials towards future commercialization. Cancer Immunotherapy Market IN8bio is tackling a large market. Grand View Research estimates that the global cancer immunotherapy market was worth approximately $115 billion in 2022 and is expected to grow at a compound annual growth rate of 8.7% from 2023 to 2030. Diving deeper, the American Cancer Society estimates that there will be 59,610 new cases of leukemia (and 23,710 deaths) in 2023, and the National Brain Tumor Society estimates that there were 13,400 new cases of glioblastoma in 2022. Despite being a lesser-known disease, awareness of glioblastoma is growing quickly. This is mainly due to the unfortunate, high-profile deaths of the President’s son, Beau Biden, and former U.S. Senator John McCain. One Step Closer Towards Cancer Zero IN8bio’s portfolio of cell therapies has the potential to offer a better treatment option for patients suffering from difficult to treat solid and liquid tumors such as AML and glioblastoma. The company’s primary advantage is its patent-protected platform gamma-delta T cell technologies, which it believes may allow it to better target cancer cells, getting deeper responses without hurting the patient’s healthy cells. The biotechnology company has had its foot on the gas pedal in recent years, boasting the following achievements: Two programs in phase 1, and enrollment has been initiated in its corporate-sponsored phase 2 trial at multiple sites across the U.S. A portfolio of preclinical programs in development including: iPSC derived gamma-delta T cells platform. iPSCs represent a significant step toward next generation approaches of cellular manufacturing for true allogeneic and potentially ‘off-the-shelf’ cellular therapies. INB-300, which focuses on addressing various solid and liquid tumors using a dedicated gamma-delta non-signaling CAR-T, or nsCAR, construct. These nsCAR constructs are designed specifically for the biology of gamma-delta T cells and allow IN8bio to potentially target tumor tissues while leaving healthy tissue alone. This could potentially create safer and more potent therapies. 19 granted patents for its technology. A brand new state-of-the-art R&D facility. $17 million in cash on hand, as of June 30, 2023, to help fund its operations and drug development. While the company is currently unprofitable – posting a net loss of $7.7 million for the three months ended June 30, 2023 – this is largely expected for biotechnology companies in the clinical development stage as they work to develop new drugs. However, IN8bio’s approach to business appears to be quite different in the biotechnology industry. The company reports it has been able to advance its clinical and preclinical programs by being extremely efficient with the capital raised, searching for innovative ways to advance their preclinical and clinical programs. Whereas IN8bio has successfully advanced multiple programs into phase 1 and 2 clinical trials while only having spent $76.5 million through 2Q23, a number of competing cell therapy companies have spent far more while showing similar, or less progress. Co-founder and CEO, William Ho has over 22 years of combined experience managing biotechnology companies, healthcare finance and investing, while co-founder and CSO, Lawrence Lamb has been in cellular therapy for three decades. They and the rest of the management team have the experience and know-how to effectively execute, manufacture, develop and advance the company’s growing portfolio of cancer therapies. With any luck, IN8bio will be able to achieve their mission of Cancer Zero, making cancer a thing of the past. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

November 06, 2023 09:00 AM Eastern Standard Time

Where Is Your Doctor Investing? Chances Are It Could Be DLP Capital – A Deep Dive Into The Returns Offered By The Firm’s Housing-Focused Funds

Benzinga

By Austin DeNoce, Benzinga Physicians, after years of intensive training and practice, are known for their rigorous and methodical approach when making decisions that impact their patients' health. This same attention to detail can often extend to their financial investments, and many are curious about where successful doctors invest their money. Treating patients, like investing, requires intelligence and patience. Among the myriad of investment choices available, DLP Capital emerges as an interesting choice due to its comparable ethos reflected in its broader vision of positively impacting society, and doctors seem to have taken notice – the company reports doctors have invested over $260 million in DLP Capital’s housing-focused funds. A Glimpse Into DLP Capital's Portfolio Since it was founded in 2006, DLP Capital has solidified its position in the investment landscape, earning a spot on the Inc. 5000 Fastest-Growing Companies list and retaining it for 11 consecutive years. The firm manages assets valued at over $5 billion, drawing support from a diverse pool of more than 2,600 investors. Owning and overseeing over 18,000 housing units, several of their funds have met or even surpassed their targeted returns. Through their varied endeavors, DLP Capital claims to have positively impacted more than 838,000 lives. Historical Returns: A Snapshot DLP Lending Fund: With a target annual return of 9-10%, this fund managed a 12.71% annual return as of September 30, 2023. As a private REIT emphasizing rental housing in high ownership-cost areas, it offers investors liquidity, a rigorous borrower vetting process and a 90-day redemption period without long-term constraints. Prioritizing investor returns, all preferred payouts are dispensed before any management fees, and invested capital retains a top-tier position, ensuring payment precedence over common equity participants. DLP Building Communities Fund: With an ambitious target of 11-13%, this fund achieved an annual return of 12.81% by the end of 2022. Designed as an evergreen private real estate fund, it focuses on developing new rental communities for attainable housing while providing a measure of protection against stock market volatility, consistent asset valuation for growth and flexible redemption options. All returns are prioritized to investors before any management fee is levied, ensuring their capital retains a preferred, high-priority position in all deals. DLP Preferred Credit Fund: This fund achieved a return of 10.52% in Q2 for 2023 on its 10-11% annual target, emphasizing insulation against rising interest rates and ensuring liquidity. By rigorously vetting borrowers and prioritizing loans to seasoned real estate sponsors, the fund ensures investors enjoy a preferred payment position and monthly returns before management fees, aligning the interests of DLP with its investors. Focusing on debt and preferred credit investments in the Sun Belt, its intent is to make a dent in America's affordable housing crisis, ensuring that rentals are attainable for working families. DLP Housing Fund: Perhaps the most eye-catching of the lot, DLP reports this fund saw an annual return of 27.04% by September 30, 2023, much higher than its annual target of 10-11%. By investing equity in multifamily rental communities (including manufactured housing and RV), the fund emphasizes both renter affordability and investor returns. The fund operates as an open-ended, private real estate venture focusing on long-term assets to yield enhanced returns. Investors not only benefit from tax advantages like depreciation offsets and 1031 tax-deferred exchanges, but they also enjoy flexible annual redemptions and a preferred position, guaranteeing payment priority over common equity investors. With returns like this, DLP may seem like a natural choice for many, but doctors are being attracted to DLP Capital for multiple reasons. The Attraction Of Passive Income One of the primary draws for busy professionals – such as those in the medical field – is the concept of passive income. They can enjoy the fruits of their investments without the daily demands of active engagement. DLP Capital's offerings, especially with its history of consistent returns, specifically aim to satisfy this demand for passive income – and doctors seem to find them particularly appealing. Impact Investing: Partnering With Doctors To Do Good Professionals like doctors frequently align their investment choices with societal benefits. Given the intrinsic desire among many in the medical profession to contribute positively to society, there's potential interest in DLP Capital, primarily due to its initiatives in affordable housing. Specifically, the DLP Housing Fund focuses on rental housing aimed at those with incomes near the area median. Likewise, the DLP Preferred Credit Fund and the DLP Building Communities Fund incorporate rental affordability into their strategies. Consequently, these funds combine financial objectives with addressing a relevant societal challenge. Exceeding Expectations DLP Capital has maintained a consistent investment record. Since its founding in 2006, there have been no reported capital losses for investors. Such reliable performance, alongside the size of potential returns, are important considerations for those evaluating investment options. Some of DLP Capital's funds have also achieved returns beyond their initial targets, reflecting reasonable success for some of its investment strategies. At the very least, their performance suggests a capacity to meet and occasionally exceed market expectations, though past performance is not a guarantee of future performance. Don Wenner, the CEO of DLP Capital, has played a significant role in the firm's direction. With over 16,000 real estate transactions amounting to more than $4 billion since 2006, his experience is extensive. Leveraging his experience, DLP's overarching mission includes both profit generation and broader goals to positively influence millions of lives. DLP Capital's Prognosis DLP Capital has positioned itself within the investment space by emphasizing passive income, societal impact and consistent returns – and successful professionals like doctors seem to be paying attention, with over a quarter of a billion invested by the medical community. The firm offers a comprehensive approach that integrates passive revenue streams, initiatives in affordable housing and a track record that reflects its strategy and performance over time. All returns aside, DLP Capital's alignment with affordable housing initiatives echoes the ethos of many in the medical profession and could be attractive to others, especially those seeking to yield a positive societal impact through their investments. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

November 06, 2023 09:00 AM Eastern Standard Time

The AI Image Generator Taking User Creativity to New Frontiers

Hotimage.AI

Artificial intelligence has amazed many with its applications in AI chat, such as ChatGPT. However, AI has also revolutionized the field of image generation. Gone are the days when users needed to spend hours on Photoshop to design a new photo. Now, they can rely on platforms that swiftly bring their ideas to life and transform them into images with the help of an AI image generator. One of the newest AI image generator platforms is hotimage.ai, this site aims to empower users to explore their creativity. It is an easy-to-use and free website where users can delve into their artistic style across various categories, including support for NSFW AI generated images. "The platform's concept is to provide users with a safe environment for crafting images from scratch, without requiring technical expertise, while ensuring that their ideas and fantasies are brought to life with the utmost realism," said Elizabeth Carter, the CEO of hotimage.ai. Key highlights of hotimage.ai include: Realistic Images: The platform creates images that appear real and precise within seconds. Hotimage.ai generates high-quality visual content, suitable for various fields like advertising, entertainment, and product design. Copyright-Free Images: Users can download and utilize images created by the platform without the need for real subjects or models. Speed and Security: The platform can generate lifelike images within seconds while ensuring complete anonymity and security. Versatility: Offering a wide range of options for image generation, hotimage.ai allows users to craft their photos and explore different styles, including animation, artistic renditions, portraits, and AI NSFW content. Using hotimage.ai is simple, just visit the website, choose the desired image category, and begin selecting from the available options. For instance, if you're creating an image featuring a model, you can select various options such as hairstyle, hair color, facial expressions, and background settings. After making your selections, click on "generate," and the platform will swiftly create the desired picture within seconds. Utilizing Artificial Intelligence, AI image generator sites offer a myriad of possibilities in various artistic styles. Users simply provide the details or a general idea, including their "must-haves," and the AI image generator will transform these instructions into a picture within seconds. Contact Details Hotimage.AI support@hotimage.ai Official Website https://hotimage.ai/ Contact Details Adam Scott +1 346-428-8364 support@hotimage.ai

November 03, 2023 10:33 AM Eastern Daylight Time

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Elicio Therapeutics (NASDAQ: ELTX) Reports Promising Progress In Cancer Vaccine Clinical Trials, Placing An Emphasis On The Lymphatic System

Benzinga

By Jeremy Golden, Benzinga An estimated 609,820 people will die of cancer in the United States this year, according to the National Cancer Institute. Promising results from a 12-year-old clinical-stage biotechnology company have experts optimistic about the future of treating this deadly disease. With its proprietary Amphiphile or “AMP” platform, Elicio Therapeutics Inc. (NASDAQ: ELTX) has developed multiple cancer vaccine candidates that concentrate an array of different immunogens in the lymph nodes. ELI-002 is Elicio’s lead clinical program for Kirsten rat sarcoma (KRAS) driven cancers caused by a mutation of the KRAS gene. An “off the shelf” approach designed to stimulate an immune response against the seven KRAS mutations driving 25% of solid tumors, ELI-002 is currently being studied in AMPLIFY-201 – a phase 1 dose escalation study – and AMPLIFY-7P, a phase 1/2 study. In September, Elicio released new information about the vaccine candidates in its pipeline at the ninth AACR Special Conference on Pancreatic Cancer in Boston. The positive preliminary relapse-free survival (RFS) data from the ongoing AMPLIFY-201 study demonstrated an 86% reduction in risk of progression or death in patients with large T-cell responses induced by ELI-002 2P, a 2-peptide formulation designed to treat cancers driven by G12D and G12R mutations in KRAS. Despite the AMPLIYF-201 study not including a control arm, the median RFS of over 16 months is significantly longer than what has been seen in other studies of similar patient groups. “Patients with mutant KRAS cancers, particularly pancreatic and colorectal cancers, have a poor prognosis with limited treatment options when tumor DNA or protein biomarkers are detected after standard surgery and chemotherapy,” said Eileen M. O’Reilly, M.D., Winthrop Rockefeller Endowed Chair of Medical Oncology and Co-Director of Medical Initiatives at David M. Rubenstein Center for Pancreatic Cancer Research. “We are encouraged by the early data showing ELI-002 induced T cells can positively impact clinical endpoints including the risk of relapse and death in this study.” Targeting Immunogens To Lymph Nodes Elicio has demonstrated preclinically that Amphiphiles target and concentrate an array of different immunogens in the lymph nodes, which are located throughout the body on the lymphatic vessels at various intervals along the lymphatic routes. During the process of circulating throughout the lymphatic system, lymph fluid accumulates antigens and other biomolecules captured from the tissues. This fluid then drains into the lymph nodes, where it encounters T cells and B cells congregating together with antigen-presenting cells (APCs). Targeting the immunogens in the lymph nodes has been proven to result in tumor or pathogen-targeted immunity, including potent T cell and humoral responses, in preclinical trials. Alongside AMPLIFY-201, ELI-002 7P is currently being studied in AMPLIFY-7P, a phase 1/2 trial in patients with high relapse risk mKRAS-driven solid tumors. Designed to provide immune response coverage against seven of the most common KRAS mutations, the ELI-002 7P formulation increases the potential patient population for ELI-002 while possibly reducing the chance of bypassing resistance mechanisms. Moving forward in early 2024, Elicio Therapeutics plans to initiate a randomized phase 2 trial studying ELI-002 7P as a monotherapy in adjuvant PDAC patients. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

November 03, 2023 09:00 AM Eastern Daylight Time

QYOU Media Appoints Former TikTok Country Manager Raj Mishra as India Group CEO Overseeing All Operations

QYOU Media

Contact Details Doug Barker +1 437-992-4814 shareholder@qyoutv.com Company Website https://www.valuethemarkets.com

November 02, 2023 12:00 PM Eastern Daylight Time

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News Release

Which Stocks Are Primed For India's HUGE Social Media Market?

QYOU Media Inc

ValueTheMarkets News Commentary - India is on course to soon become the planet's biggest social media market, with the country gaining some serious ground on China. According to Statista, India's 1.18 billion unique users will be just 33 million behind the top spot. This article examines who is seeking to capitalize on this huge market with reference to Meta Platforms Inc (NASDAQ: META), Snap Inc (NYSE: SNAP), Alphabet (NASDAQ: GOOGL) and QYOU Media (TSXV: QYOU) (OTC: QYOUF). Meta Platforms enjoys a dominant position in terms of platforms and uses India to test out new monetization strategies. Alphabet has an already hugely successful product in the country, and one of its features looks set to go from strength to strength. Finally, Snap is seeking to leverage its massive audience in the country. QYOU Media (TSXV: QYOU) (OTC: QYOUF) produces and distributes content created by social media stars. It has a multitude of TV channels and platforms and is attracting a rapidly growing audience. Now, the business has brought in bonafide social media royalty to push it to the next stage. It has appointed Indian digital leader and strategist, Raj Mishra, to the role of Group CEO of its India operations. Mishra has held leading roles in some of the most successful app businesses in India. This includes an instrumental role at Musical.ly (now TikTok), leading it to over 150 million monthly active users. He served as Country Head and led Musical.ly to become the most downloaded app on Android and iOS app stores. He oversaw the rebranding transition from musical.ly to TikTok after its 2017 acquisition wherein it racked up 611 million downloads in under three years. Meta Platforms Inc (NASDAQ: META) is dominant in the Indian social media market. The company's flagship Facebook app has a 55% market share in the country, according to data from July 2023 provided by Statista. Additionally, the same source has its Instagram app as the second biggest platform in the country, with a market share of 36%. Such is the might of the platforms that they have both been confident enough to launch new paid subscription services for Indian users who want an ad-free experience. This is symptomatic of how the company has been operating Facebook, Instagram and WhatsApp in the country, with the Financial Times noting that India is often used as something of a testing ground. As well as introducing subscription fees, innovations include click-to-message ad formats. These connect customers and businesses within various chat applications, with the company taking home commission from all business done via the route. Alphabet (NASDAQ: GOOGL) has a huge interest in Indian social network users too. That's because India is the largest audience for the company's YouTube video sharing and social media platform. Data from Statista shows that 462 million Indians tuned in to YouTube in October 2023, with the United States in a distant second place with 236 million. What this tells us is that India is hugely important for YouTube and, by extension, its parent company. The business has a major edge in the country too. With Chinese mega-app TikTok having been banned in India three years ago, the short-form video content space is missing a major competitor. YouTube's "Shorts" feature is going a long way to filling this void, helping the company to maintain its huge numbers of viewers in the country. Snap Inc (NYSE: SNAP) is another business we must discuss when touching on short-form video. Snap has also become hugely popular in India, with figures from Statista showing that its user base is 59% higher than that of the United States. If nothing else, this is a testament to how crazy about social media the Indian population is! But there is still room to grow, according to forecasts. Projections from Statista indicate that, following a ninth consecutive annual increase in user base, the platform will reach 158.63 million users and therefore a new peak in 2027. But how is the company seeking to capitalize on this user base? Like QYOU Media, the company has recently appointed an industry star to run its Indian operations in the form of former Google executive Pulkit Trivedi. With sagging revenues, the app is reportedly targeting India for new growth amid efforts to localize services and shore up ad revenues. India is a massive prospect for social media-savvy companies. But there are multiple routes to taking advantage of this exciting opportunity. QYOU Media has achieved consistent quarterly YoY revenue growth and has brought in a social media whiz to push things to the next level. Meta Platforms is rolling out subscription fees and new ad technology, while Alphabet is taking advantage of short-form video. Finally, Snap is trying to solve the puzzle of its lagging revenues through localization. IMPORTANT NOTICE AND DISCLAIMER PAID ADVERTISEMENT This communication is a paid advertisement. ValueTheMarkets is a trading name of Digitonic Ltd, and its owners, directors, officers, employees, affiliates, agents and assigns (collectively the "Publisher") is often paid by one or more of the profiled companies or a third party to disseminate these types of communications. In this case, the Publisher has been compensated by QYOU Media Inc. to conduct investor awareness advertising and marketing and has paid the Publisher the equivalent of one hundred and twenty five thousand US dollars to produce and disseminate this and other similar articles and certain related banner advertisements. This compensation should be viewed as a major conflict with the Publisher's ability to provide unbiased information or opinion. 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November 02, 2023 11:00 AM Eastern Daylight Time

Dashtoon secures $5M to bring comic creation to the masses

Dashtoon

The advent of text-to-image AI diffusion models uncovered a promising opportunity for the digital comics landscape, akin to the transformative impact of high-quality camera phones and the rise of platforms like Instagram and TikTok. Now, Dashtoon is on a mission to make this cutting-edge technology accessible to storytellers worldwide, aiming to democratize the creation of digital comics and empower creators across the globe with its Dashtoon AI Studio and Dashtoon Comic Reader Apps. Today, Dashtoon is announcing a $5 million seed funding led by Matrix Partners India and Stellaris Venture Partners with participation from prominent angel investors. San Francisco and London-based Dashtoon was founded in December 2022 by Sanidhya Narain, Lalith Gudipati, and Soumyadeep Mukherjee. Lalith and Sanidhya were both part of the founding team of audio entertainment startup Pocket FM and were instrumental in building and growing the product in the US. Soumyadeep has built and scaled deep-tech teams at various startups including solving for cancer diagnosis at Morphle Labs. A vibrant creator economy for the comics ecosystem exists in markets like Japan and Southeast Asia but not so much in the other parts of the world. Consequently, Japanese Manga and Korean Webtoons have now ascended to the forefront, asserting their dominance over the global comics market while nurturing billion-dollar IPs - replicated into multiple formats like games, movies, TV series, etc. Beyond storytelling, till now, comic creation required hard skills like sketching, coloring, lettering, etc., thus creating an entry barrier for this medium. The current creator ecosystems were built over decades, and it wasn’t possible to replicate them in other parts of the world. But now, with Dashtoon, any storyteller, from published author to aspiring writer, in any part of the world, can effortlessly create, distribute, and monetize their comics and graphic novels - the age of democratization. "Content businesses have largely capitalized on technology for distribution. We at Dashtoon believe it's time to bring that technological edge to content creation itself. Generative AI will not only level the playing field for storytellers worldwide but will also meet the diverse tastes of global consumers.” says Sanidhya Narain, CEO and Co-founder of Dashtoon. Dashtoon Studio, the first of its kind, guarantees unparalleled character consistency, fine control over image composition, and streamlined comic creation workflows. This state-of-the-art platform provides creators access to an extensive character library and the capability to train and monetize their unique characters, enabling the production of professional-quality, engaging content ready for global consumption. “With Dashtoon Studio, any storyteller, regardless of their artistic skills or technical knowledge, can create digital comics, breaking traditional barriers in illustrated content creation. Our vision is to become a global IP powerhouse by marrying thousands of creators with millions of readers,” says Soumyadeep Mukherjee, CTO and Co-founder. For example, a creator can upload their storyboard on Dashtoon Studio, select characters for each panel, and generate images with deterministic and consistent output in a few minutes. The creator can use smart AI editing capabilities in the studio to edit the generated output. What used to take 40-50 hours to create an episode can currently be done in 5-6 hours, thus allowing creators to publish a new episode daily on Dashtoon Comic Reader apps. With further advancement, Dashtoon will add multi-modal capabilities to generate storyboards and dialogues using AI, further reducing the creation time of an episode to less than an hour. Dashtoon Studio is a valuable tool that complements the creative process, empowering creators to unleash their imagination and craft compelling narratives without being bogged down by repetitive, time-consuming tasks. A synergy between technology and creativity paves the way for innovative storytelling and content creation. Dashtoon Comic Reader Apps are a cornerstone for writers desiring to broaden their horizons, offering an invaluable opportunity to penetrate the thriving comics market. For consumers - this means that they do not have to wait weeks for new episodes of their favorite comics - with the increase in content creation speed, they get new episodes daily on Dashtoon Comic Reader. Due to non-existent native creator ecosystems - consumers were mostly limited in choices to consume Japanese manga or Korean webtoons, but now they will get enough native content that is culturally contextual and curated to their choices. “Dashtoon’s mission is to create a world where the art of comic creation is as widespread and culturally ingrained as it is in places like Japan and Korea,” says Lalith Gudipati, COO and Co-founder. “We are thrilled to pioneer a movement that integrates technology and creativity, bringing forth a global creative renaissance in digital comics.” The goal is to build an ecosystem that not only boosts the artistic capabilities and productivity of creators but enables them to monetize their content on Day 1. The readers can access these titles with ease and a user-friendly interface on Dashtoon Comic Reader. With GenAI, the comic book industry has become a greenfield market. Smartphones will become even smarter and more powerful, and the creation will come to mobile devices. This will lead to constant innovations and new formats with a bustling creator-consumer economy, and Dashtoon aims to be at the forefront of it. This funding round will enable Dashtoon to deepen its AI research, progress product development, and content production in the coming months. Naman Lahoty, Principal at Stellaris Venture Partners added: "Content consumption on mobile phones has grown exponentially in the US, from an average of 45 minutes per day in 2011 to a staggering 4 hours per day in 2021. This surge has been fueled by the emergence of new and diverse content formats like short-form videos, audio OTT, podcasts, and casual games that have captivated consumers. Looking ahead, we anticipate that webcomics will emerge as the next wave of growth. As pioneers in this domain, Dashtoon is poised to lead the charge with the founders possesing a perfect mix of content, tech and global user acquisition experience and skills required to build this business.” Aakash Kumar, Managing Director at Matrix Partners India said: “Over several decades content distribution has gone through a phase shift driven by technology, yet we have seen little on the front of content creation being disrupted. In the coming years, the business of content will undergo many transformations and the most important of those is going to be creation getting democratized and boundaries between PGC and UGC getting blurred, and content choices for consumers growing multifold and becoming extensively personalized. We are excited to be partnering with Dashtoon team on their journey to shape this future vision of content.” About Dashtoon Dashtoon is a revolutionary platform that leverages Generative AI technology to enable storytellers worldwide to create illustrated content with unprecedented ease and speed. Dashtoon is curating the best stories globally and visualizing them into comics and graphic novels. Users can discover dazzling universes soaring beyond superheroes and clichés! A realm awaits. It’s as if Manga and HBO teamed up to craft spellbinding comics. For more information, please visit https://dashtoon.com/ About Matrix Partners India Founded in 2006, Matrix Partners India invests in companies targeting the consumer and enterprise market at the seed, early and early growth stages. The firm has invested in several enterprise technology companies such as MoEngage (Customer engagement platform), Toddle (Teaching & learning platform), SuperOps.ai (AI-powered PSA-RMM platform), Rocketlane (Customer onboarding platform), Murf AI (Synthetic speech technology), 100ms (Live video infrastructure) and Atomicwork (Employee success solution) amongst others. Other marquee investments include Dailyhunt (Local language platform), Five Star Business Finance (SME lending), OfBusiness (B2B commerce, fintech), Ola (Mobility), Ola Electric (Electric vehicles), OneCard (Mobile-first credit card), Oxyzo (Tech-enabled smart financing), Razorpay (Payments), Country Delight (D2C dairy & fresh foods brand), GoKwik (E-commerce enablement platform), Jupiter (Neobank), and Mosaic Wellness (Health & wellness), among others. Matrix Partners India has advisory offices in Bangalore, Delhi and Mumbai. Further information is available at www.matrixpartners.in. To know more about our investment philosophy & ideologies, check out the #MatrixMoments podcast series. About Stellaris Venture Partners Stellaris is an early-stage tech-focused VC firm that partners with fearless founders who dream big, think differently, and have an unstoppable desire to challenge the status quo. The fund works with these teams at nascent stages to help transform their ideas into resilient businesses. Stellaris does so with a team of seasoned, diverse operators and entrepreneurs who bring significant experience in building businesses and by providing access to some of the most successful founders and professionals. Since its inception in 2017, Stellaris has backed many market leaders such as Mamaearth, Whatfix, Propelld, Turno, Rigi, and others. For more information on Stellaris Venture Partners, visit https://www.stellarisvp.com. Contact Details Dashtoon Bilal Mahmood +44 7714 007257 b.mahmood@stockwoodstrategy.com Company Website https://dashtoon.com/

November 02, 2023 09:00 AM Eastern Daylight Time

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